Technology Applications

Without an application, a technology would be nothing. We encourage you to explore some of our projects below and see for yourself how Salus Discovery is applying our technology to solve both local and global issues.

Salus Discovery improving tuberculosis diagnostics in developing countries. Mill and Melinda Gates Foundation. Tuberculosis Test

IMPROVING TUBERCULOSIS DIAGNOSTICS IN DEVELOPING COUNTRIES

Tuberculosis (TB) is a prominent and life-threatening disease particularly in underdeveloped countries where methods to monitor and detect TB are limited. Salus Discovery is spearheading a project to develop a low-cost, simple TB diagnostic to make TB tests available to those that need it the most. (Funded by the Bill and Melinda Gates Foundation)

Enhanced Monitoring of HIV

The latent viral reservoir is a major barrier to eradicating HIV infection. Unfortunately, very few tools are available to quantify the reservoir and monitor the effectiveness of prospective therapies that aim to reduce it. In response, Salus Discovery is leveraging our microfluidic KOALATM technology to develop an assay platform that is easy to use and highly repeatable, critical requirements for successful clinical implementation (Funded by the National Intitutes of Health (NIH))
Salus Discovery is applying ESP to isolate circulating tumor cells (CTCs) from whole blood

Isolation of circulating tumor cells to advance cancer diagnostics

Circulating tumor cells (CTCs) are a rare cell population, which circulate through the bloodstream and migrate into surrounding tissue to form new metastases. Salus Discovery uses the ESPTM technology to isolate CTCs. These CTCs - through genetic, transcriptomic, and proteomic signatures - provide information that may help guide cancer monitoring and treatment. (Funded by the National Intitutes of Health (NIH)). (View Financial Conflict of Interest Documentation)

 
Salus Discovery is developing and testing a ESP based low-cost HIV viral load assay

Low-cost HIV Viral Load

When it comes to evaluating a technology, there is no substitute for in-country, hands-on experience. In collaboration with the Joint Clinical Research Centre (JCRC) (Kampala, Uganda), Salus Discovery is working to develop an affordable ESP HIV viral load assay. (Funded by the Government of Uganda)

 
Salus Discovery is developing an ESP based technology for isolating protein complexes

WEAK BINDING PROTEINS: USING ESP TO SEE THE UNSEEN

Proteins are a predominant method of intra- and inter-cellular communication. Many proteins form complexes - complexes that play a critical role in regulating cellular biology. Assessment of these complexes has the potential to lead to the discovery of new drugs and bio-markers. Using the unique advantages of ESP, we are able to capture intact protein complexes to fully evaluate their potential as new drug targets. What will be discovered next? (Funded by the National Intitutes of Health (NIH))